![]() ![]() Very rare (less than 0.01%): Movement disorder, ataxia, dizziness, seizure, anterograde amnesiaįrequency not reported: Involuntary movements, hyperactivity, decreased alertness, somnolence, prolonged/postoperative sedation, convulsions/drug withdrawal convulsions, feeling faint, tonic/clonic movements and muscle tremor Postmarketing reports: Acid taste, excessive salivation, retching, toothache Nervous systemĬommon (1% to 10%): Sedation/prolonged sedation, somnolence, depressed levels of consciousnessįrequency not reported: Drooling, dizziness, ataxia, vertigo, dysarthria, loss of balanceĬommon (1% to 10%): Headache, oversedation, drowsiness, seizure-like activity Very rare (less than 0.01%): Constipation, dry mouth Very common (10% or more): Emesis/vomiting (up to 11%)įrequency not reported: Gagging, salivation Respiratory adverse events included hypoxia, laryngospasm, rhonchi, coughing, respiratory depression, airway obstruction, upper airway congestion, and shallow respirations these side effects occurred more frequently at higher doses.ĭecreased tidal volume/respiratory rate occurred in 23.3% of patients given IV formulations and in 10.8% of patients given IM formulations.Īpnea occurred in 15.4% of patients given IV formulations. Postmarketing reports: Bronchospasm, hyperventilation, wheezing, shallow respirations, airway obstruction, tachypnea, dysphonia, yawning, continued phonation Very rare (less than 0.01%): Dyspnea, hiccup, laryngospasm, respiratory arrestįrequency not reported: Respiratory depression Very common (10% or more): Decreased tidal volume/respiratory rate (up to 23.3%), apnea (up to 15.4%)Ĭommon (1% to 10%): Hiccoughs, coughing, desaturation Uncommon (0.1% to 1%): Sneezing/rhinorrheaįrequency not reported: Apnea, hypercarbia, desaturation, stridor, hiccough Very common (10% or more): Respiratory adverse events (up to 11%)Ĭommon (1% to 10%): Respiratory depression, hypoxia, laryngospasm, upper airway obstruction, rhonchi, congestion Decreased tidal volume/respiratory rate and apnea were most commonly reported with parenteral formulations. The most commonly reported side effects with oral formulations include emesis and nausea. Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection siteĪpplies to midazolam: compounding powder, injectable solution, intramuscular solution, intravenous solution, nasal spray, oral syrup.Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of midazolam may occur that usually do not need medical attention. unsteadiness, trembling, or other problems with muscle control or coordination.changes in patterns and rhythms of speech.Get emergency help immediately if any of the following symptoms of overdose occur while taking midazolam: Symptoms of overdose unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness.difficulty walking, speaking, or writing.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor or nurse immediately if any of the following side effects occur while taking midazolam: Less common Serious side effects of VersedĪlong with its needed effects, midazolam (the active ingredient contained in Versed) may cause some unwanted effects. Midazolam injection should not be administered by rapid injection in the neonatal population as severe hypotension and seizures have been reported. The initial dose and all subsequent doses should always be titrated slowly. Use only in settings that can provide for continuous monitoring of respiratory and cardiac function. Midazolam has been associated with respiratory depression and respiratory arrest, especially when used for sedation in noncritical care settings. ![]()
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